Borane-protected phosphines are redox-active radioprotective agents for endothelial cells

Exposure to radiation can damage endothelial cells in the irradiated area via the production of reactive oxygen species. We synthesized phosphine–borane complexes that reduce disulfide bonds and had previously been shown to interfere with redox-mediated signaling of cell death. We hypothesized that...

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Detalles Bibliográficos
Publicado en:Redox Biol
Main Authors: Crowe, Megan E., Lieven, Christopher J., Thompson, Alex F., Sheibani, Nader, Levin, Leonard A.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513185/
https://ncbi.nlm.nih.gov/pubmed/26188467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.06.015
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