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NEU1 Sialidase Regulates Membrane-tethered Mucin (MUC1) Ectodomain Adhesiveness for Pseudomonas aeruginosa and Decoy Receptor Release

Airway epithelia express sialylated receptors that recognize exogenous danger signals. Regulation of receptor responsiveness to these signals remains incompletely defined. Here, we explore the mechanisms through which the human sialidase, neuraminidase-1 (NEU1), promotes the interaction between the...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lillehoj, Erik P., Hyun, Sang Won, Liu, Anguo, Guang, Wei, Verceles, Avelino C., Luzina, Irina G., Atamas, Sergei P., Kim, K. Chul, Goldblum, Simeon E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513093/
https://ncbi.nlm.nih.gov/pubmed/25963144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.657114
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