Early-onset Crohn’s disease and autoimmunity associated with a variant in CTLA-4

OBJECTIVE: IBD is a group of complex, systemic disorders associated with intestinal inflammation and extraintestinal manifestations. Recent studies revealed Mendelian forms of IBD, which contributed significantly to our understanding of disease pathogenesis and the heritability of IBD. DESIGN: We pe...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Zeissig, Sebastian, Petersen, Britt-Sabina, Tomczak, Michal, Melum, Espen, Huc-Claustre, Emilie, Dougan, Stephanie K, Laerdahl, Jon K, Stade, Björn, Forster, Michael, Schreiber, Stefan, Weir, Dascha, Leichtner, Alan M, Franke, Andre, Blumberg, Richard S
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512923/
https://ncbi.nlm.nih.gov/pubmed/25367873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-308541
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