Early-onset Crohn’s disease and autoimmunity associated with a variant in CTLA-4

OBJECTIVE: IBD is a group of complex, systemic disorders associated with intestinal inflammation and extraintestinal manifestations. Recent studies revealed Mendelian forms of IBD, which contributed significantly to our understanding of disease pathogenesis and the heritability of IBD. DESIGN: We pe...

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Vydáno v:Gut
Hlavní autoři: Zeissig, Sebastian, Petersen, Britt-Sabina, Tomczak, Michal, Melum, Espen, Huc-Claustre, Emilie, Dougan, Stephanie K, Laerdahl, Jon K, Stade, Björn, Forster, Michael, Schreiber, Stefan, Weir, Dascha, Leichtner, Alan M, Franke, Andre, Blumberg, Richard S
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512923/
https://ncbi.nlm.nih.gov/pubmed/25367873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-308541
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