A carregar...
mTOR kinase structure, mechanism and regulation by the rapamycin-binding domain
The mammalian target of rapamycin (mTOR), a phosphoinositide 3-kinase related protein kinase, controls cell growth in response to nutrients and growth factors and is frequently deregulated in cancer. Here we report co-crystal structures of a truncated mTOR-mLST8 complex with an ATP transition state...
Na minha lista:
| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4512754/ https://ncbi.nlm.nih.gov/pubmed/23636326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12122 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|