Ocular Inserts for Sustained Release of the Angiotensin-Converting Enzyme 2 Activator, Diminazene Aceturate, to Treat Glaucoma in Rats

The aim of this study was to develop and evaluate the effects of chitosan inserts for sustained release of the angiotensin-converting enzyme 2 (ACE2) activator, diminazene aceturate (DIZE), in experimental glaucoma. Monolayer DIZE loaded inserts (D+I) were prepared and characterized through swelling...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Foureaux, Giselle, Franca, Juçara Ribeiro, Nogueira, José Carlos, Fulgêncio, Gustavo de Oliveira, Ribeiro, Tatiana Gomes, Castilho, Rachel Oliveira, Yoshida, Maria Irene, Fuscaldi, Leonardo Lima, Fernandes, Simone Odília Antunes, Cardoso, Valbert Nascimento, Cronemberger, Sebastião, Faraco, André Augusto Gomes, Ferreira, Anderson José
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512709/
https://ncbi.nlm.nih.gov/pubmed/26204514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133149
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