Bimatoprost-Loaded Ocular Inserts as Sustained Release Drug Delivery Systems for Glaucoma Treatment: In Vitro and In Vivo Evaluation

The purpose of the present study was to develop and assess a novel sustained-release drug delivery system of Bimatoprost (BIM). Chitosan polymeric inserts were prepared using the solvent casting method and characterized by swelling studies, infrared spectroscopy, differential scanning calorimetry, d...

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Detalhes bibliográficos
Main Authors: Franca, Juçara Ribeiro, Foureaux, Giselle, Fuscaldi, Leonardo Lima, Ribeiro, Tatiana Gomes, Rodrigues, Lívia Bomfim, Bravo, Renata, Castilho, Rachel Oliveira, Yoshida, Maria Irene, Cardoso, Valbert Nascimento, Fernandes, Simone Odília, Cronemberger, Sebastião, Ferreira, Anderson José, Faraco, André Augusto Gomes
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4005758/
https://ncbi.nlm.nih.gov/pubmed/24788066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095461
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