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Angiotensin-Converting Enzyme 2 (ACE2) Activator Diminazene Aceturate Ameliorates Endotoxin-Induced Uveitis in Mice

PURPOSE. Uveitis is a common cause of vision loss. The renin angiotensin system (RAS), which plays a vital role in cardiovascular system, is a potent mediator of inflammation and has been implicated in the pathogenesis of uveitis. A newly identified axis of RAS, ACE2/Ang-(1-7)/Mas, has emerged as a...

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Détails bibliographiques
Auteurs principaux: Qiu, Yiguo, Shil, Pollob Kumar, Zhu, Ping, Yang, Hongxia, Verma, Amrisha, Lei, Bo, Li, Qiuhong
Format: Artigo
Langue:Inglês
Publié: The Association for Research in Vision and Ophthalmology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062403/
https://ncbi.nlm.nih.gov/pubmed/24854854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-13883
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