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Fine Mapping Causal Variants with an Approximate Bayesian Method Using Marginal Test Statistics

Two recently developed fine-mapping methods, CAVIAR and PAINTOR, demonstrate better performance over other fine-mapping methods. They also have the advantage of using only the marginal test statistics and the correlation among SNPs. Both methods leverage the fact that the marginal test statistics as...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Chen, Wenan, Larrabee, Beth R., Ovsyannikova, Inna G., Kennedy, Richard B., Haralambieva, Iana H., Poland, Gregory A., Schaid, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512539/
https://ncbi.nlm.nih.gov/pubmed/25948564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.176107
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