Wird geladen...

Incorporating Functional Annotations for Fine-Mapping Causal Variants in a Bayesian Framework Using Summary Statistics

Functional annotations have been shown to improve both the discovery power and fine-mapping accuracy in genome-wide association studies. However, the optimal strategy to incorporate the large number of existing annotations is still not clear. In this study, we propose a Bayesian framework to incorpo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Genetics
Hauptverfasser: Chen, Wenan, McDonnell, Shannon K., Thibodeau, Stephen N., Tillmans, Lori S., Schaid, Daniel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105870/
https://ncbi.nlm.nih.gov/pubmed/27655946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.188953
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!