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From genome-wide associations to candidate causal variants by statistical fine-mapping

Advancing from statistical associations of complex traits with genetic markers to understanding the functional genetic variants that influence traits is often a complex process. Fine-mapping can select and prioritize genetic variants for further study, yet the multitude of analytical strategies and...

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Detalhes bibliográficos
Publicado no:Nat Rev Genet
Main Authors: Schaid, Daniel J., Chen, Wenan, Larson, Nicholas B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050137/
https://ncbi.nlm.nih.gov/pubmed/29844615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41576-018-0016-z
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