H3K36 methylation promotes longevity by enhancing transcriptional fidelity

Epigenetic mechanisms, including histone post-translational modifications, control longevity in diverse organisms. Relatedly, loss of proper transcriptional regulation on a global scale is an emerging phenomenon of shortened life span, but the specific mechanisms linking these observations remain to...

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Vydáno v:Genes Dev
Hlavní autoři: Sen, Payel, Dang, Weiwei, Donahue, Greg, Dai, Junbiao, Dorsey, Jean, Cao, Xiaohua, Liu, Wei, Cao, Kajia, Perry, Rocco, Lee, Jun Yeop, Wasko, Brian M., Carr, Daniel T., He, Chong, Robison, Brett, Wagner, John, Gregory, Brian D., Kaeberlein, Matt, Kennedy, Brian K., Boeke, Jef D., Berger, Shelley L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511212/
https://ncbi.nlm.nih.gov/pubmed/26159996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.263707.115
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