Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism

Histone acetylations are important epigenetic markers for transcriptional activation in response to metabolic changes and various stresses. Using the high-throughput SEquencing-Based Yeast replicative Lifespan screen method and the yeast knockout collection, we demonstrate that the HDA complex, a cl...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Yu, Ruofan, Cao, Xiaohua, Sun, Luyang, Zhu, Jun-yi, Wasko, Brian M, Liu, Wei, Crutcher, Emeline, Liu, Haiying, Jo, Myeong Chan, Qin, Lidong, Kaeberlein, Matt, Han, Zhe, Dang, Weiwei
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8012573/
https://ncbi.nlm.nih.gov/pubmed/33790287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22257-2
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky