Cloning and Initial Functional Characterization of Mlk4α and Mlk4β

We have cloned a novel human mixed-lineage kinase gene, MLK4. Two alternatively spliced forms, MLK4α (580 aa) and MLK4β (1036 aa), have been identified and mapped to chromosomal band 1q42. MLK4 shows high amino acid homology to the kinase catalytic domain of MLK3 (72%), MLK1 (71%) and MLK2 (69%). St...

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Veröffentlicht in:Genomics Insights
Hauptverfasser: Kashuba, Vladimir I, Grigorieva, Elvira V, Kvasha, Sergei M, Pavlova, Tatiana V, Grigoriev, Vladimir, Protopopov, Alexei, Kharchenko, Olga, Gizatullin, Rinat, Rynditch, Alla V, Zabarovsky, Eugene R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Libertas Academica 2011
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510602/
https://ncbi.nlm.nih.gov/pubmed/26217104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/GEI.S6092
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