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NKG2D Signaling Leads to NK Cell Mediated Lysis of Childhood AML

Natural killer cells have been shown to be relevant in the recognition and lysis of acute myeloid leukemia. In childhood acute lymphoblastic leukemia, it was shown that HLA I expression and KIR receptor-ligand mismatch significantly impact ALL cytolysis. We characterized 14 different primary childho...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Schlegel, Patrick, Ditthard, Kerstin, Lang, Peter, Mezger, Markus, Michaelis, Sebastian, Handgretinger, Rupert, Pfeiffer, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510257/
https://ncbi.nlm.nih.gov/pubmed/26236752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/473175
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