c-Myc regulates expression of NKG2D ligands ULBP1/2/3 in AML and modulates their susceptibility to NK-mediated lysis

Cytarabine (cytosine arabinoside) is one of the most effective drugs for the treatment of patients diagnosed with acute myeloid leukemia (AML). Despite its efficiency against AML cells, the emergence of drug resistance due to prolonged chemotherapy in most patients is still a major obstacle. Several...

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Autores principales: Nanbakhsh, Arash, Pochon, Cécile, Mallavialle, Aude, Amsellem, Sophie, Bourhis, Jean Henri, Chouaib, Salem
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2014
Materias:
Immunobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198341/
https://ncbi.nlm.nih.gov/pubmed/24677544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-11-536219
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