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HIF-2α/ITPR1 axis: A new saboteur of NK-mediated lysis

We recently investigated the role of von Hippel-Lindau (VHL) mutation and the subsequent induction of hypoxia-inducible factor 2α (HIF-2α) in the regulation of renal cell carcinoma (RCC) susceptibility to natural killer (NK) cell-mediated killing. We demonstrated that the resistance of VHL-mutated R...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Messai, Yosra, Noman, Muhammad Zaeem, Hasmim, Meriem, Escudier, Bernard, Chouaib, Salem
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404821/
https://ncbi.nlm.nih.gov/pubmed/25949883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/2162402X.2014.985951
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