Dynamic changes in replication timing and gene expression during lineage specification of human pluripotent stem cells

Duplication of the genome in mammalian cells occurs in a defined temporal order referred to as its replication-timing (RT) program. RT changes dynamically during development, regulated in units of 400–800 kb referred to as replication domains (RDs). Changes in RT are generally coordinated with trans...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genome Res
Prif Awduron: Rivera-Mulia, Juan Carlos, Buckley, Quinton, Sasaki, Takayo, Zimmerman, Jared, Didier, Ruth A., Nazor, Kristopher, Loring, Jeanne F., Lian, Zheng, Weissman, Sherman, Robins, Allan J., Schulz, Thomas C., Menendez, Laura, Kulik, Michael J., Dalton, Stephen, Gabr, Haitham, Kahveci, Tamer, Gilbert, David M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2015
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509994/
https://ncbi.nlm.nih.gov/pubmed/26055160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.187989.114
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