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Molecular modeling of the binding modes of the Iron-sulfur protein to the Jac1 co-chaperone from Saccharomyces cerevisiae by all-atom and coarse-grained approaches

The Iron sulfur protein 1 (Isu1) from yeast, and the J-type co-chaperone Jac1, are part of a huge ATP-dependent system, and both interact with Hsp70 chaperones. Interaction of Isu1 and Jac1 is a part of the iron-sulfur cluster biogenesis system in mitochondria. In this study, the structure and dynam...

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Detalhes bibliográficos
Publicado no:Proteins
Main Authors: Mozolewska, Magdalena A., Krupa, Paweł, Scheraga, Harold A., Liwo, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509829/
https://ncbi.nlm.nih.gov/pubmed/25973573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24824
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