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PDZ binding to the BAR domain of PICK1 is elucidated by coarse-grained molecular dynamics
A key regulator of AMPA (α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid) receptor traffic, PICK1 is also known to interact with over 40 other proteins, including receptors, transporters, and ionic channels, and to be active mostly as a homodimer. The current lack of a complete PICK1 structure...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3008210/ https://ncbi.nlm.nih.gov/pubmed/21050858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.10.051 |
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