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MicroRNA-199a* regulates the expression of cyclooxygenase-2 in human chondrocytes

OBJECTIVE: Cyclooxygenase-2 (COX-2) expression is associated with the pathogenesis of chronic inflammation and pain in osteoarthritis (OA). A study was undertaken to determine whether interleukin-1β (IL-1β)-mediated induction of COX-2 can be regulated by microRNAs (miRNAs) in OA. METHODS: Human chon...

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Dades bibliogràfiques
Publicat a:Ann Rheum Dis
Autors principals: Akhtar, Nahid, Haqqi, Tariq M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509731/
https://ncbi.nlm.nih.gov/pubmed/22294637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2011-200519
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