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MicroRNA-9 promotes IL-6 expression by inhibiting MCPIP1 expression in IL-1β-stimulated human chondrocytes
OBJECTIVE: Enhanced IL-6 expression plays an important role in the pathogenesis of osteoarthritis (OA). MCPIP1 is a novel post-transcriptional regulator of IL-6 expression and is targeted by miR-9. We investigated the MCPIP1 expression in OA cartilage and explored whether targeting of MCPIP1 by miR-...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Arthritis Rheumatol |
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| Κύριοι συγγραφείς: | , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4519390/ https://ncbi.nlm.nih.gov/pubmed/25917063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39173 |
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