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MicroRNA-27b Regulates the Expression of Matrix Metalloproteinase 13 in Human Osteoarthritis Chondrocytes

OBJECTIVE: Aberrant posttranscriptional regulation of matrix metalloproteinases (MMPs) by microRNA has emerged as an important factor in human diseases. The aim of this study was to determine whether the expression of MMP-13 in human osteoarthritis (OA) chondrocytes is regulated by microRNA. METHODS...

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Detalhes bibliográficos
Main Authors: Akhtar, Nahid, Rasheed, Zafar, Ramamurthy, Sangeetha, Anbazhagan, Arivarasu N., Voss, Frank R., Haqqi, Tariq M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139404/
https://ncbi.nlm.nih.gov/pubmed/20131257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27329
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