Pomegranate extract inhibits the interleukin-1β-induced activation of MKK-3, p38α-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes

INTRODUCTION: Pomegranate has been revered throughout history for its medicinal properties. p38-MAPK is a major signal-transducing pathway in osteoarthritis (OA) and its activation by interleukin-1β (IL-1β) plays a critical role in the expression and production of several mediators of cartilage cata...

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Hlavní autoři: Rasheed, Zafar, Akhtar, Nahid, Haqqi, Tariq M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991031/
https://ncbi.nlm.nih.gov/pubmed/20955562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3166
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