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Pomegranate extract inhibits the interleukin-1β-induced activation of MKK-3, p38α-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes
INTRODUCTION: Pomegranate has been revered throughout history for its medicinal properties. p38-MAPK is a major signal-transducing pathway in osteoarthritis (OA) and its activation by interleukin-1β (IL-1β) plays a critical role in the expression and production of several mediators of cartilage cata...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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BioMed Central
2010
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2991031/ https://ncbi.nlm.nih.gov/pubmed/20955562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3166 |
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