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Role of apolipoprotein E in neurodegenerative diseases
Apolipoprotein E (APOE) is a lipid-transport protein abundantly expressed in most neurons in the central nervous system. APOE-dependent alterations of the endocytic pathway can affect different functions. APOE binds to cell-surface receptors to deliver lipids and to the hydrophobic amyloid-β peptide...
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| Publicado no: | Neuropsychiatr Dis Treat |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4509527/ https://ncbi.nlm.nih.gov/pubmed/26213471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S84266 |
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