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Role of apolipoprotein E in neurodegenerative diseases

Apolipoprotein E (APOE) is a lipid-transport protein abundantly expressed in most neurons in the central nervous system. APOE-dependent alterations of the endocytic pathway can affect different functions. APOE binds to cell-surface receptors to deliver lipids and to the hydrophobic amyloid-β peptide...

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Publicat a:Neuropsychiatr Dis Treat
Autors principals: Giau, Vo Van, Bagyinszky, Eva, An, Seong Soo A, Kim, Sang Yun
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509527/
https://ncbi.nlm.nih.gov/pubmed/26213471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S84266
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