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Role of apolipoprotein E in neurodegenerative diseases
Apolipoprotein E (APOE) is a lipid-transport protein abundantly expressed in most neurons in the central nervous system. APOE-dependent alterations of the endocytic pathway can affect different functions. APOE binds to cell-surface receptors to deliver lipids and to the hydrophobic amyloid-β peptide...
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| 出版年: | Neuropsychiatr Dis Treat |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Dove Medical Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4509527/ https://ncbi.nlm.nih.gov/pubmed/26213471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S84266 |
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