Macroautophagy is essential for killing of intracellular Burkholderia pseudomallei in human neutrophils

Neutrophils play a key role in the control of Burkholderia pseudomallei, the pathogen that causes melioidosis. Here, we show that survival of intracellular B. pseudomallei was significantly increased in the presence of 3-methyladenine or lysosomal cathepsin inhibitors. The LC3-flux was increased in...

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Bibliografske podrobnosti
izdano v:Autophagy
Main Authors: Rinchai, Darawan, Riyapa, Donporn, Buddhisa, Surachat, Utispan, Kusumawadee, Titball, Richard W, Stevens, Mark P, Stevens, Joanne M, Ogawa, Michinaga, Tanida, Isei, Koike, Masato, Uchiyama, Yasuo, Ato, Manabu, Lertmemongkolchai, Ganjana
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Translational Brief Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509438/
https://ncbi.nlm.nih.gov/pubmed/25996656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1040969
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