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CIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface
Members of the transforming growth factor β (TGFβ) family initiate cellular responses by binding to TGFβ receptor type II (TβRII) and type I (TβRI) serine/threonine kinases, whereby Smad2 and Smad3 are phosphorylated and activated, promoting their association with Smad4. We report here that TβRI int...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4508896/ https://ncbi.nlm.nih.gov/pubmed/26169354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201411025 |
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