CIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface

Members of the transforming growth factor β (TGFβ) family initiate cellular responses by binding to TGFβ receptor type II (TβRII) and type I (TβRI) serine/threonine kinases, whereby Smad2 and Smad3 are phosphorylated and activated, promoting their association with Smad4. We report here that TβRI int...

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Vydáno v:J Cell Biol
Hlavní autoři: Yakymovych, Ihor, Yakymovych, Mariya, Zang, Guangxiang, Mu, Yabing, Bergh, Anders, Landström, Maréne, Heldin, Carl-Henrik
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2015
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508896/
https://ncbi.nlm.nih.gov/pubmed/26169354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201411025
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