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Pro-invasive properties of Snail1 are regulated by sumoylation in response to TGFβ stimulation in cancer
Transforming growth factor β (TGFβ) is a key regulator of epithelial-to-mesenchymal transition (EMT) during embryogenesis and in tumors. The effect of TGFβ, on ΕΜΤ, is conveyed by induction of the pro-invasive transcription factor Snail1. In this study, we report that TGFβ stimulates Snail1 sumoylat...
में बचाया:
| में प्रकाशित: | Oncotarget |
|---|---|
| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Impact Journals LLC
2017
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5716685/ https://ncbi.nlm.nih.gov/pubmed/29228645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20097 |
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