The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity

Lipid metabolism and receptor-mediated signaling are highly intertwined processes that cooperate to fulfill cellular functions and safeguard cellular homeostasis. Activation of Toll-like receptors (TLRs) leads to a complex cellular response, orchestrating a diverse range of inflammatory events that...

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Pubblicato in:Cell Rep
Autori principali: Heinz, Leonhard X., Baumann, Christoph L., Köberlin, Marielle S., Snijder, Berend, Gawish, Riem, Shui, Guanghou, Sharif, Omar, Aspalter, Irene M., Müller, André C., Kandasamy, Richard K., Breitwieser, Florian P., Pichlmair, Andreas, Bruckner, Manuela, Rebsamen, Manuele, Blüml, Stephan, Karonitsch, Thomas, Fauster, Astrid, Colinge, Jacques, Bennett, Keiryn L., Knapp, Sylvia, Wenk, Markus R., Superti-Furga, Giulio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508342/
https://ncbi.nlm.nih.gov/pubmed/26095358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.006
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