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Integrating Multiple Correlated Phenotypes for Genetic Association Analysis by Maximizing Heritability

Many correlated disease variables are analyzed jointly in genetic studies in the hope of increasing power to detect causal genetic variants. One approach involves assessing the relationship between each phenotype and each single nucleotide polymorphism (SNP) individually and using a Bonferroni corre...

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Bibliografiske detaljer
Udgivet i:Hum Hered
Main Authors: Zhou, Jin J., Cho, Michael H., Lange, Christoph, Lutz, Sharon, Silverman, Edwin K., Laird, Nan M.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508328/
https://ncbi.nlm.nih.gov/pubmed/26111731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000381641
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