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Boosting heritability: estimating the genetic component of phenotypic variation with multiple sample splitting

BACKGROUND: Heritability is a central measure in genetics quantifying how much of the variability observed in a trait is attributable to genetic differences. Existing methods for estimating heritability are most often based on random-effect models, typically for computational reasons. The alternativ...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Mai, The Tien, Turner, Paul, Corander, Jukka
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004405/
https://ncbi.nlm.nih.gov/pubmed/33773584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-021-04079-7
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