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Transgenic Mice Overexpressing Serum Retinol-Binding Protein Develop Progressive Retinal Degeneration through a Retinoid-Independent Mechanism

Serum retinol-binding protein 4 (RBP4) is the sole specific transport protein for retinol in the blood, but it is also an adipokine with retinol-independent, proinflammatory activity associated with obesity, insulin resistance, type 2 diabetes, and cardiovascular disease. Moreover, two separate stud...

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Publicado en:Mol Cell Biol
Main Authors: Du, Mei, Otalora, Laura, Martin, Ashley A., Moiseyev, Gennadiy, Vanlandingham, Phillip, Wang, Qilong, Farjo, Rafal, Yeganeh, Alexander, Quiambao, Alexander, Farjo, Krysten M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508322/
https://ncbi.nlm.nih.gov/pubmed/26055327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00181-15
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