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Cytosolic chloride ion is a key factor in lysosomal acidification and function of autophagy in human gastric cancer cell

The purpose of the present study was to clarify roles of cytosolic chloride ion (Cl(−)) in regulation of lysosomal acidification [intra-lysosomal pH (pH(lys))] and autophagy function in human gastric cancer cell line (MKN28). The MKN28 cells cultured under a low Cl(−) condition elevated pH(lys) and...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Hosogi, Shigekuni, Kusuzaki, Katsuyuki, Inui, Toshio, Wang, Xiangdong, Marunaka, Yoshinori
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508152/
https://ncbi.nlm.nih.gov/pubmed/24725767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12257
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