Respiratory syncytial virus-like nanoparticle vaccination induces long-term protection without pulmonary disease by modulating cytokines and T-cells partially through alveolar macrophages

The mechanisms of protection against respiratory syncytial virus (RSV) are poorly understood. Virus-like nanoparticles expressing RSV glycoproteins (eg, a combination of fusion and glycoprotein virus-like nanoparticles [FG VLPs]) have been suggested to be a promising RSV vaccine candidate. To unders...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Nanomedicine
Hauptverfasser: Lee, Young-Tae, Ko, Eun-Ju, Hwang, Hye Suk, Lee, Jong Seok, Kim, Ki-Hye, Kwon, Young-Man, Kang, Sang-Moo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2015
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508085/
https://ncbi.nlm.nih.gov/pubmed/26203246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S83493
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