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Structural characterization of the interaction of Ubp6 with the 26S proteasome

In eukaryotic cells, the 26S proteasome is responsible for the regulated degradation of intracellular proteins. Several cofactors interact transiently with this large macromolecular machine and modulate its function. The deubiquitylating enzyme ubiquitin C-terminal hydrolase 6 [Ubp6; ubiquitin-speci...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Aufderheide, Antje, Beck, Florian, Stengel, Florian, Hartwig, Michaela, Schweitzer, Andreas, Pfeifer, Günter, Goldberg, Alfred L., Sakata, Eri, Baumeister, Wolfgang, Förster, Friedrich
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507206/
https://ncbi.nlm.nih.gov/pubmed/26130806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510449112
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