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Structural characterization of the interaction of Ubp6 with the 26S proteasome

In eukaryotic cells, the 26S proteasome is responsible for the regulated degradation of intracellular proteins. Several cofactors interact transiently with this large macromolecular machine and modulate its function. The deubiquitylating enzyme ubiquitin C-terminal hydrolase 6 [Ubp6; ubiquitin-speci...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Aufderheide, Antje, Beck, Florian, Stengel, Florian, Hartwig, Michaela, Schweitzer, Andreas, Pfeifer, Günter, Goldberg, Alfred L., Sakata, Eri, Baumeister, Wolfgang, Förster, Friedrich
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507206/
https://ncbi.nlm.nih.gov/pubmed/26130806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510449112
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