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FUS functions in coupling transcription to splicing by mediating an interaction between RNAP II and U1 snRNP
Pre-mRNA splicing is coupled to transcription by RNA polymerase II (RNAP II). We previously showed that U1 small nuclear ribonucleoprotein (snRNP) associates with RNAP II, and both RNAP II and U1 snRNP are also the most abundant factors associated with the protein fused-in-sarcoma (FUS), which is mu...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4507187/ https://ncbi.nlm.nih.gov/pubmed/26124092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506282112 |
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