Evidence that U5 snRNP recognizes the 3' splice site for catalytic step II in mammals.

The first AG dinucleotide downstream from the branchpoint sequence (BPS) is chosen as the 3' splice site during catalytic step II of the splicing reaction. The mechanism and factors involved in selection of this AG are not known. Early in mammalian spliceosome assembly, U2AF65 binds to the pyri...

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Bibliographic Details
Main Authors: Chiara, M D, Palandjian, L, Feld Kramer, R, Reed, R
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170101/
https://ncbi.nlm.nih.gov/pubmed/9303319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.15.4746
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