Mechanism of influenza A M2 transmembrane domain assembly in lipid membranes

M2 from influenza A virus functions as an oligomeric proton channel essential for the viral cycle, hence it is a high-priority pharmacological target whose structure and functions require better understanding. We studied the mechanism of M2 transmembrane domain (M2TMD) assembly in lipid membranes by...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Georgieva, Elka R., Borbat, Peter P., Norman, Haley D., Freed, Jack H.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507135/
https://ncbi.nlm.nih.gov/pubmed/26190831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11757
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