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Protein Oxidation in Aging: Does It Play a Role in Aging Progression?
Significance: A constant accumulation of oxidized proteins takes place during aging. Oxidation of proteins leads to a partial unfolding and, therefore, to aggregation. Protein aggregates impair the activity of cellular proteolytic systems (proteasomes, lysosomes), resulting in further accumulation o...
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| 出版年: | Antioxid Redox Signal |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Mary Ann Liebert, Inc.
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4507125/ https://ncbi.nlm.nih.gov/pubmed/25178482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2014.6062 |
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