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Protein Oxidation in Aging: Does It Play a Role in Aging Progression?

Significance: A constant accumulation of oxidized proteins takes place during aging. Oxidation of proteins leads to a partial unfolding and, therefore, to aggregation. Protein aggregates impair the activity of cellular proteolytic systems (proteasomes, lysosomes), resulting in further accumulation o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antioxid Redox Signal
Egile Nagusiak: Reeg, Sandra, Grune, Tilman
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Mary Ann Liebert, Inc. 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507125/
https://ncbi.nlm.nih.gov/pubmed/25178482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2014.6062
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