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The molecular chaperone Hsp70 promotes the proteolytic removal of oxidatively damaged proteins by the proteasome

One hallmark of aging is the accumulation of protein aggregates, promoted by the unfolding of oxidized proteins. Unraveling the mechanism by which oxidized proteins are degraded may provide a basis to delay the early onset of features, such as protein aggregate formation, that contribute to the agin...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Free Radic Biol Med
Κύριοι συγγραφείς: Reeg, Sandra, Jung, Tobias, Castro, José P., Davies, Kelvin J.A., Henze, Andrea, Grune, Tilman
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201141/
https://ncbi.nlm.nih.gov/pubmed/27498116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.08.002
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