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The molecular chaperone Hsp70 promotes the proteolytic removal of oxidatively damaged proteins by the proteasome

One hallmark of aging is the accumulation of protein aggregates, promoted by the unfolding of oxidized proteins. Unraveling the mechanism by which oxidized proteins are degraded may provide a basis to delay the early onset of features, such as protein aggregate formation, that contribute to the agin...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Free Radic Biol Med
मुख्य लेखकों: Reeg, Sandra, Jung, Tobias, Castro, José P., Davies, Kelvin J.A., Henze, Andrea, Grune, Tilman
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201141/
https://ncbi.nlm.nih.gov/pubmed/27498116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.08.002
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