Probing the target search of DNA-binding proteins in mammalian cells using TetR as model searcher

Many cellular functions rely on DNA-binding proteins finding and associating to specific sites in the genome. Yet the mechanisms underlying the target search remain poorly understood, especially in the case of the highly organized mammalian cell nucleus. Using as a model Tet repressors (TetRs) searc...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Normanno, Davide, Boudarène, Lydia, Dugast-Darzacq, Claire, Chen, Jiji, Richter, Christian, Proux, Florence, Bénichou, Olivier, Voituriez, Raphaël, Darzacq, Xavier, Dahan, Maxime
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Pub. Group 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507003/
https://ncbi.nlm.nih.gov/pubmed/26151127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8357
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