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Regulation of the Epigenome by Vitamin C
Emerging evidence suggests that ascorbate, the dominant form of vitamin C under physiological pH conditions, influences the genome activity via regulating epigenomic processes. Ascorbate serves as a cofactor for ten-eleven translocation (TET) dioxygenases that catalyze the oxidation of 5-methylcytos...
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| Publicat a: | Annu Rev Nutr |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506708/ https://ncbi.nlm.nih.gov/pubmed/25974700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-nutr-071714-034228 |
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