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Regulation of the Epigenome by Vitamin C
Emerging evidence suggests that ascorbate, the dominant form of vitamin C under physiological pH conditions, influences the genome activity via regulating epigenomic processes. Ascorbate serves as a cofactor for ten-eleven translocation (TET) dioxygenases that catalyze the oxidation of 5-methylcytos...
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Publicado no: | Annu Rev Nutr |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506708/ https://ncbi.nlm.nih.gov/pubmed/25974700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-nutr-071714-034228 |
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