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Regulation of the Epigenome by Vitamin C

Emerging evidence suggests that ascorbate, the dominant form of vitamin C under physiological pH conditions, influences the genome activity via regulating epigenomic processes. Ascorbate serves as a cofactor for ten-eleven translocation (TET) dioxygenases that catalyze the oxidation of 5-methylcytos...

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Foilsithe in:Annu Rev Nutr
Main Authors: Young, Juan I., Züchner, Stephan, Wang, Gaofeng
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506708/
https://ncbi.nlm.nih.gov/pubmed/25974700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-nutr-071714-034228
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