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Dual Binding of an Antibody and a Small Molecule Increases the Stability of TERRA G-Quadruplex**
In investigating the binding interactions between the human telomeric RNA (TERRA) G-quadruplex (GQ) and its ligands, it was found that the small molecule carboxypyridostatin (cPDS) and the GQ-selective antibody BG4 simultaneously bind the TERRA GQ. We previously showed that the overall binding affin...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
WILEY-VCH Verlag
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506565/ https://ncbi.nlm.nih.gov/pubmed/25421962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201408113 |
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