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Drug Screening Boosted by Hyperpolarized Long-Lived States in NMR
Transverse and longitudinal relaxation times (T(1ρ) and T(1)) have been widely exploited in NMR to probe the binding of ligands and putative drugs to target proteins. We have shown recently that long-lived states (LLS) can be more sensitive to ligand binding. LLS can be excited if the ligand compris...
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| Yayımlandı: | ChemMedChem |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
WILEY-VCH Verlag
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506523/ https://ncbi.nlm.nih.gov/pubmed/25196781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201402214 |
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