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Human Upf1 is a highly processive RNA helicase and translocase with RNP remodelling activities
RNA helicases are implicated in most cellular RNA-dependent events. In eukaryotes however, only few have been functionally characterized. Upf1 is a RNA helicase essential for nonsense-mediated mRNA decay (NMD). Here, using magnetic tweezers and bulk assays, we observe that human Upf1 is able to tran...
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| Published in: | Nat Commun |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Pub. Group
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506499/ https://ncbi.nlm.nih.gov/pubmed/26138914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8581 |
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